HydroKarma Serum

Amniotic fluid is a treasure trove of bioactive compounds with exceptional regenerative and rejuvenating properties. HydroKarma™ Serum is a refined, pure, and unadulterated formulation of human amniotic fluid. Meticulously processed, it preserves perinatal exosomes and extracellular matrix proteins, harnessing the power of this natural elixir to deliver unparalleled skincare benefits.

Packed with Perinatal Exosomes Naturally Infused with Rejuvenating Factors

    1. Epidermal Growth Factor (EGF):

      • Function: Stimulates cell growth, proliferation, and differentiation.

      • Benefits: Promotes skin regeneration, improves texture, and reduces wrinkles.

    2. Fibroblast Growth Factor 2 (FGF-2, bFGF):

      • Function: Encourages fibroblast proliferation and differentiation.

      • Benefits: Essential for collagen production and skin repair, enhancing wound healing and skin rejuvenation.

    3. Transforming Growth Factor-beta 1 (TGF-beta 1):

      • Function: Regulates cell growth and differentiation, stimulates collagen production.

      • Benefits: Supports extracellular matrix formation, vital for maintaining skin structure and elasticity.

    4. Vascular Endothelial Growth Factor (VEGF):

      • Function: Promotes angiogenesis, improving blood supply to the skin.

      • Benefits: Enhances nutrient delivery and waste removal, contributing to healthier, more radiant skin.

    5. Insulin-like Growth Factor 1 (IGF-1):

      • Function: Supports cell growth and development, has anti-apoptotic effects.

      • Benefits: Regenerates skin cells and maintains skin thickness and elasticity.

    1. hsa-mir-21:

      • Function: Enhances cell survival and promotes skin cell proliferation while reducing cell death.

      • Benefits: Supports the repair and renewal of skin, leading to a more youthful and revitalized appearance.

    2. hsa-let-7b:

      • Function: Regulates cell differentiation and proliferation.

      • Benefits: Helps maintain skin structure and smoothness, promoting a rejuvenated and refreshed complexion.

    3. hsa-mir-34c:

      • Function: Controls cell growth and promotes the natural turnover of skin cells.

      • Benefits: Ensures the removal of old cells and the regeneration of new, healthy skin cells, resulting in fresher, healthier-looking skin.

    4. hsa-mir-125a:

      • Function: Modulates inflammatory responses and promotes a balanced skin environment.

      • Benefits: Reduces inflammation, achieving a clearer and more even skin tone, enhancing overall skin health and appearance.

    5. hsa-mir-126:

      • Function: Enhances blood vessel formation and improves nutrient delivery to the skin.

      • Benefits: Supports better skin repair and regeneration, leading to a more vibrant, youthful, and radiant complexion.

Harnessing Amnniotic Fluid’s Rejuvenating Potenial

  • Perinatal Exosomes

    HydroKarma Serum is an amniotic fluid-derived biomaterial (AFdB), carefully processed to preserve vital perinatal exosomes . These exosomes contain key proteins like EGF, FGF-2, and TGF-beta 1 that work synergistically to stimulate collagen production, cell proliferation, and skin repair, supporting skin rejuvenation at the cellular level. These exosomes also contain beneficial microRNAs such as hsa-mir-21 and hsa-let-7b that regulate cell differentiation and survival, promoting a more youthful and revitalized appearance.

  • Extracellular Matrix Proteins

    The processing technology employed in manufacture of HydroKarma Serum enhances the concentration of exosomes and seamlessly integrates essential extracellular matrix (ECM) proteins. This optimizes the biomaterial's ability to enhance skin rejuvenation.

  • Rejuvenation Therapy Application

    HydroKarma Serum can be used pre- or post-treatment to enhance the effectiveness of cosmetic procedures, such as laser treatments, chemical peels, and microneedling. The serum's nourishing properties help prepare the skin for these interventions, leading to improved outcomes and faster recovery times. The serum's rejuvenating properties help soothe and nourish the skin, reducing inflammation and promoting a faster, more effective recovery post treatment.

Setting New Standards for Rejuvenation Aesthetics

Enhanced Safety Profile

A comprehensive testing regime including microbial, endotoxin, sterility, human adventitious viruses and sub-visible particulate analysis ensures the highest standards of purity, sterility, and bioactivity.

Uncompromising Quality

Advanced analytical technologies are employed to confirm the identity and assess the structural integrity, uniformity, consistency, potency and functionality of the exosomes in HydroKarma Serum, as well as the ECM proteins in every batch.

Premium. In Every Way

The choice of high-quality glass vials with industry-leading low particle levels and minimal product-container interaction minimize the risk of chemical interactions between the container and the product, ensuring the bioactivity and purity of the serum.